Recent advances in network-based methods for disease gene prediction
نویسندگان
چکیده
منابع مشابه
Recent Advances in Hemophilia Gene Therapy
Heterogeneous loss of function mutations at F8 and F9 genes causes X-linked recessive bleeding disorders, hemophilia A (HA) and hemophilia B (HB), respectively. HA is clinically indistinguishable from HB and accounts for more than 80% of hemophilia cases; the former affects 1/5000 and the latter 1/25000 male births worldwide. In Iran, it is estimated that around 4300 HA and 900 HB patients are ...
متن کاملNetwork-based methods for human disease gene prediction.
Despite the considerable progress in disease gene discovery, we are far from uncovering the underlying cellular mechanisms of diseases since complex traits, even many Mendelian diseases, cannot be explained by simple genotype-phenotype relationships. More recently, an increasingly accepted view is that human diseases result from perturbations of cellular systems, especially molecular networks. ...
متن کاملRecent advances in gene structure prediction.
De novo gene predictors are programs that predict the exon-intron structures of genes using the sequences of one or more genomes as their only input. In the past two years, dual-genome de novo predictors, which exploit local rates and patterns of mutation inferred from alignments between two genomes, have led to significant improvements in accuracy. Systems that exploit more than two genomes si...
متن کاملRecent advances in extraction methods of medicinal plant components
Various novel techniques including ultrasound-assisted extraction, microwave-assisted extraction and supercritical fluid extraction have been developed for the extraction of medicinal plants in order to shorten the extraction time, decrease the solvent consumption, increase the extraction yield, and enhance the quality of extracts. This review was conducted to introduce and compare the conventi...
متن کاملRecent advances in extraction methods of medicinal plant components
Various novel techniques including ultrasound-assisted extraction, microwave-assisted extraction and supercritical fluid extraction have been developed for the extraction of medicinal plants in order to shorten the extraction time, decrease the solvent consumption, increase the extraction yield, and enhance the quality of extracts. This review was conducted to introduce and compare the conventi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Briefings in Bioinformatics
سال: 2020
ISSN: 1467-5463,1477-4054
DOI: 10.1093/bib/bbaa303